EmuNations

Playnite is an open source video game library manager with support for 3rd party libraries like Steam, GOG, Origin, Battle.net and Uplay. While providing one unified interface for your games, it includes game emulation support, fullscreen mode, themes and much more.

Requires Windows 7+ and .NET Framework 4.6 

WineD3D For Windows is a DirectX 1-11 to OpenGL wrapper with almost full implementation of DirectX used in Wine. Even if Windows supports DirectX natively, using WineD3D can enhance backwards compatibility with older games, especially on Windows 8+ that don't support 16-bit screen modes. Others possible values include eliminating unsupported versions of DirectX, or porting DirectX applications to OpenGL without having to rewrite the rendering code. That said, it's far from perfect... 

Wine (Wine Is Not an Emulator) is a compatibility-layer capable of running Windows applications on several POSIX-compliant systems such as Linux, macOS & BSD.

Instead of simulating internal Windows logic like a virtual machine, Wine translates Windows API-calls into POSIX-calls on-the-fly, thus eliminating performance and memory penalties and allowing you to cleanly integrate Windows applications into your desktop.

Ruffle is a Flash Player emulator written in Rust. Ruffle runs natively on all modern operating systems as a standalone application, and on all modern browsers through the use of WebAssembly and has extensive content compatibility in ActionScript; the language that powers interactivity in games and applications made with Flash.

Users or website owners may install the web version of Ruffle and existing flash content will "just work", with no extra configuration required. It will also detect all existing Flash content and this is an entirely open source project maintained by volunteers.

DXVK provides a Vulkan-based translation layer for D3D9, D3D10, D3D11 & D3D12. It can be used on Linux with Wine to allow running 3D apps and games designed for Windows on GNU/Linux systems through Wine...

D8VK: An implementation of Direct3D 8 for DXVK. 

• Check here for me details..

Also, note Vulkan 1.3 is a firm requirement and wine 7.1 or newer.

VirtualBox is a powerful x86 and AMD/Intel64 virtualization solution for home and enterprise usage. It's quite feature rich, high performance yet is freely available as an Open Source Software. While it's mainly a community effort, Oracle is backing it to ensure it maintains high standards of quality.

Presently, it runs on Windows, Linux, Macintosh, and Solaris hosts and supports a large number of guest operating systems including but not limited to Windows (NT 4.0+, DOS/Windows 3.x, Linux (2.4, 2.6, 3.x and 4.x), Solaris and OpenSolaris, OS/2, and OpenBSD.

JoyToKey  enables PC game controllers to emulate the keyboard and mouse input, so that windows applications and web games can be controlled with your joysticks. Whenever buttons and sticks are pressed on the controllers, JoyToKey converts them into keyboard strokes and/or mouse movements so that the target application will work as if a real keyboard and a mouse were used.

AppleWin (also known as Apple //e Emulator for Windows) is an open source 

software emulator for running Apple II programs in Microsoft Windows. 

It support most programs that could run either on the Apple II+ or the Apple IIe. 

For its other capabilities, please check this reference.